منابع مشابه
Ai's Hall of Fame
AI’sHall of Fame In 2010, as the part of the celebration of the 25th anniversary of IEEE Intelligent Systems magazine, our editorial and advisory boards decided to launch the IEEE Intelligent Systems Hall of Fame to express our appreciation and respect for the trailblazers who have made significant contributions to the field of AI and intelligent systems and to honor them for their notable impa...
متن کاملRac and Rho
How were they discovered? The first Rho gene was discovered by mistake, in 1985, by a group trying to clone a homologue of the α subunit of human chorionic gonadotropin from the sea snail Aplysia. Using the Aplysia Rho sequence, three closely related mammalian genes were cloned, now called RhoA, RhoB and RhoC. Rac was first identified as a substrate for the C3 transferase that modifies Rho (alt...
متن کاملRac Downregulates Rho Activity
Using biochemical assays to determine the activation state of Rho-like GTPases, we show that the guanine nucleotide exchange factor Tiam1 functions as a specific activator of Rac but not Cdc42 or Rho in NIH3T3 fibroblasts. Activation of Rac by Tiam1 induces an epithelial-like morphology with functional cadherin-based adhesions and inhibits migration of fibroblasts. This epithelial phenotype is ...
متن کاملIFORS' Operational Research Hall of Fame
Key positions: Operations Analyst, U.S. Army, Ft. Monroe, Virginia (1955–56); Assistant Professor of Operations Research, Case Western Reserve University, Cleveland, Ohio (1957–60); Associate Professor of Operations Research, Case Western Reserve University (1960–62); Associate Professor of Operations Research and Management, Sloan School, M.I.T. (1962– 67); Professor of Operations Research and...
متن کاملTeaching Statistical Thinking Using the Baseball Hall of Fame
Baseball is a natural context in which to learn about statistics. Our national pastime is replete with averages and percentages, counts and amounts, and totals of all kind. To the fan, these are not mere numbers, but condensed stories, instantly intelligible as the true literature of the game. Compared to more fluid sports such as football, basketball, hockey, and soccer, baseball especially le...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2006
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.0000216039.75913.9e